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The HEALTH AND HUMAN SERVICES, DEPARTMENT OF | NATIONAL INSTITUTES OF HEALTH has issued a Tender notice for the procurement of a Exosome Purification, Exosomal Rna Purification, and Small Rnasequencing Services in the USA. This Tender notice was published on 27 Jun 2026 and is scheduled to close on 07 Jul 2026, with an estimated Tender value of Refer Document. Interested bidders can access detailed Tender information, eligibility criteria, and complete bidding documents by referencing TOT Ref No. 144101640, while the tender notice number is 75N98026Q00707 and Registering on the platform.
Procurement Summary
Country: USA
Summary: Exosome Purification, Exosomal Rna Purification, and Small Rnasequencing Services
Deadline: 07 Jul 2026
Posting Date: 27 Jun 2026
Other Information
Notice Type: Tender
TOT Ref.No.: 144101640
Document Ref. No.: 75N98026Q00707
Competition: ICB
Financier: Self Financed
Purchaser Ownership: Public
Tender Value: Refer Document
Purchaser's Detail
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Login to see detailsTender Details
Requirements:
BACKGROUND
With collaboration with the National Institute on Alcohol Abuse and Alcoholism (NIAAA), The National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), requires laboratory services in support of a clinical research study (POTS) in the laboratory of Dr. Paule V. Joseph at the NIH (Building 10, Bethesda, Maryland). The study requires processing of plasma specimens from 31 enrolled human research participants to isolate intact exosomes, purify exosomal RNA, and perform small RNA-sequencing for downstream analysis. These time-sensitive, irreplaceable specimens must be professionally processed to preserve sample integrity and yield analysis-ready data. The requiring laboratory does not have the in-house validated workflow or capacity to perform integrated exosome isolation, exosomal RNA purification, and Illumina small RNA-sequencing to the required standard within the necessary timeframe. The acquisition is therefore pursued to obtain these specialized services from a qualified provider so that the study's analyses can proceed without loss of specimen integrity or previously collected clinical data.
SCOPE OF WORK/TASKS
The contractor shall furnish all labor, equipment, instrumentation, reagents, and materials necessary to isolate intact exosomes, purify exosomal RNA, and perform small RNA-sequencing on the 31 Government-furnished plasma specimens, maintaining specimen integrity and chain of custody throughout.
The following tasks are required for this requirement:
Purify intact exosomes from 0.5 mL of plasma for each of 31 samples; split the elution into aliquots A and B, and further split aliquot A into two intact-exosome aliquots (two vials per sample returned to the client).
Purify exosomal RNA from intact exosomes (aliquot B); elute into two RNA aliquots per sample (one returned to the client and one used for small RNA-sequencing); perform QC of th...
Notice ID: 75n98026q00707
Department/Ind. Agency: health and human services, department of
Sub-tier: national institutes of health
Office: national institutes of health olao
Product Service Code: q301 - reference laboratory testing
NAICS Code: 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Inactive Dates: jul 08, 2026
Inactive Policy: manual
Documents
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