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The EUROPEAN FOOD SAFETY AUTHORITY (EFSA) has issued a Tender notice for the procurement of a Implementation of a Multi-Omics Workflow to Derive Human Reference Points and Health-Based Guidance Values (Hbgvs) from Quantitative in Vitro Data in the Italy. This Tender notice was published on 25 Oct 2022 and is scheduled to close on 25 Oct 2023, with an estimated Tender value of EUR 3000000.00. Interested bidders can access detailed Tender information, eligibility criteria, and complete bidding documents by referencing TOT Ref No. 73595422, while the tender notice number is 586361-2022 and Registering on the platform.
Procurement Summary
Country: Italy
Summary: Implementation of a Multi-Omics Workflow to Derive Human Reference Points and Health-Based Guidance Values (Hbgvs) from Quantitative in Vitro Data
Deadline: 25 Oct 2023
Posting Date: 25 Oct 2022
Other Information
Notice Type: Tender
TOT Ref.No.: 73595422
Document Ref. No.: 586361-2022
Competition: ICB
Financier: European Food Safety Authority (EFSA)
Purchaser Ownership: Public
Tender Value: EUR 3000000.00
CPV Classification
73000000 - Research and development services and related consultancy servicesPurchaser's Detail
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Login to see detailsTender Details
The overarching goal of the project is to define, validate and apply a standardised workflow (experimental and computational) for deriving reliable human reference points and health-based guidance values (HBGVs) using cutting edge in-vitro approaches, namely organ-on-chip (OoC) platforms and multiple OMICs endpoints (transcriptomics, metabolomics, and epigenomics). The newly generated data will be used to develop and train a bioinformatics pipeline suitable to predict mechanistic information such as mode of action (MoA), adverse outcome pathways (AOP), key biomarkers, in-vivo reference points (using IVIVE-PBK modelling) and health-based guidance values (HBGV). In phase two, the experimental and bioinformatics workflow, defined and tested in phase one, will be used to predict the aforementioned reference points and mechanistic information for a new set of emerging hazardous substances or substances with positive health claims related to food and feed.
Doc Title: Implementation of a Multi-OMICs Workflow to Derive Human Reference Points and Health-based Guidance Values (HBGVs) from Quantitative in Vitro Data
Contract Type: Services
Document Type : Prior information notice without call for competition
Reference Number : 2022/S 206-586361
Contract Type : Services
Estimated Value : 3000000.00 - EUR
73000000 - Research and development services and related consultancy services
Authority Type : European Institution/Agency or International Organisation
Type of Procedure : Not applicable
Regulation : European Institution/Agency or International Organisation
Bid Type : Not applicable
Doc Title : Implementation of a Multi-OMICs Workflow to Derive Human Reference Points and Health-based Guidance Values (HBGVs) from Quantitative in Vitro Data
Dispatch Date : 2022-10-18
Publish Date : 2022-10-25
Submission Date : 2023-10-25
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