Procurement Summary
Country : Italy
Summary : Development of in Silico Methodologies to Predict the Toxicity of Proteins in Food and Feed Risk Assessment
Deadline : 18 May 2022
Other Information
Notice Type : Tender
TOT Ref.No.: 53165770
Document Ref. No. : 248738-2021
Financier : European Food Safety Authority (EFSA)
Purchaser Ownership : -
Tender Value : EUR 200000.00
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Document Type : Prior information notice without call for competition
Title : Development of in Silico Methodologies to Predict the Toxicity of Proteins in Food and Feed Risk Assessment
Reference Number : 2021/S 095-248738
Contract Type : Services
Estimated Value : 200000.00 - EUR
Description : The target of the work is to explore in silico methodologies to predict protein toxicity, and to identify candidate approaches to be implemented as tools supporting food/feed risk assessment. The implementation of the identified methodology is not part of this call. In silico methodologies to consider can span from ‘traditional- sequence similarity analysis to artificial intelligence (e.g. machine learning, deep learning). Approaches should search for structural and functional homology of the protein of interest to toxic proteins; and/or for the presence in the protein itself of ‘toxic molecular signatures-, i.e. structural/functional properties relevant in the molecular initiating events leading to toxicity. The identified methodologies should allow to predict the potential toxicity of a protein of interest, and to infer the elicited type of toxicity, the toxicity mechanisms and the potential target tissue/s. A proposal for defining threshold criteria should be identified.
73000000 - Research and development services and related consultancy services
Authority Type : European Institution/Agency or International Organisation
Type of Procedure : Not a...
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