Purchase, Installation and Training for equipment to perform single cell spacial... Tender

Procurement Summary

Country: USA

Summary: Purchase, Installation and Training for equipment to perform single cell spacial transcriptomic visualization spanning

Deadline: 04 Aug 2025

Other Information

Notice Type: Tender

TOT Ref.No.: 123339494

Document Ref. No.: NIH-NIA-NOI-25-006884

Financier: Self Financed

Purchaser Ownership: Public

Tender Value: Refer Document

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Tender Details

Description

Spatial transcriptomics is increasingly utilized to identify transcriptional patterns within spatially-resolved areas of tissues, offering a spatial cellular context that is not achievable with bulk or single-cell RNA sequencing. Given that the pathophysiological changes involved in Alzheimer's Disease and other aging-related chronic conditions are not well understood, improved characterization of altered cellular interactions and disease states using the MERSCOPE Ultra will be crucial and this enhanced capability will help pinpoint intervention targets for multiple research experiments. On behalf of the National Institute on Aging (NIA), the National Institute on Drug Abuse (NIDA), Office of Acquisitions, intends to solicit on a sole-source basis by a request for quotation to Vizgen to acquire an upgraded Vizgen MERSCOPE instrument (MERSCOPE ULTRA). This upgrade will enable scanning of larger tissue sections at a much faster rate and facilitate the storage and analysis of data from multiple runs directly on the instrument. This enhancement is intended to meet the increased throughput demands of spatial transcriptomics samples for the NIA-IRP

The Computational Biology and Genomics Core (CBGC) of the Laboratory of Genetics and Genomics (LGG) at the National Institute on Aging (NIA) previously purchased the Vizgen MERSCOPE. To protect the integrity of ongoing experiments, it is essential that the upgraded microscope remain a Vizgen MERSCOPE.

In addition, the unique essential characteristics of the Vizgen MERSCOPE Ultra that limit the availability to a sole source are: Support for two, interchangeable flow cell sizes leading to optimized cost per sample. Maximum imageable area of 3.0cm2 which is deal for large samples or multiple smaller samples. Optimized optical design and high-performance analysis computer and data storage. Multiplexing capabilities up to 1000 plex gene panel. On-Instrument Storage Capacity of 58TB. Analysis PC Storage Capacit...
Active Contract Opportunity
Notice ID : NIH-NIA-NOI-25-006884
Related Notice
Department/Ind. Agency : HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier : NATIONAL INSTITUTES OF HEALTH
Office: NATIONAL INSTITUTES OF HEALTH NIDA
General Information
Contract Opportunity Type: Presolicitation (Original)
Original Published Date: Jul 24, 2025 01:22 pm EDT
Original Response Date: Aug 04, 2025 11:00 am EDT
Inactive Policy: 15 days after response date
Original Inactive Date: Aug 19, 2025
Initiative: None

Classification
Original Set Aside: No Set aside used
Product Service Code: 6632 - ANALYSIS INSTRUMENTS, MEDICAL LABORATORY USE
NAICS Code: 334516 - Analytical Laboratory Instrument Manufacturing

Place of Performance: Baltimore, MD 21224 USA

Documents

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