Procurement Summary
Country: Uzbekistan
Summary: Purchase of Imiglucerase 400 Tb (Effect Unit) for the Republican Specialized Pediatric Scientific and Applied Medical Center
Deadline: 20 Aug 2026
Posting Date: 05 Aug 2026
Other Information
Notice Type: Tender
TOT Ref.No.: 146588695
Document Ref. No.: 26111006505757
Competition: ICB
Financier: Self Financed
Purchaser Ownership: Public
Tender Value: UZS 26990000004.24
Purchaser's Detail
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Tender Details
Field of application It is used for long-term enzyme replacement therapy in patients with a confirmed diagnosis of Gaucher's disease. The active substance - imiglucerase - a modified form of beta-glucocerebrosidase obtained by recombinant means is the form Imiglucerase hydrolyzes glucosylceramide, compensates for enzyme deficiency and affects the main pathophysiological mechanisms of the disease. Treatment with imiglucerase leads to a decrease in the size of the spleen and liver, platelets and helps to increase or normalize hemoglobin values, improve bone mineral density, reduce bone marrow infiltration and bone pain. Treatment of glucosylceramide accumulation in macrophages and response to therapy can reduce the level of chitotriosidase, which is a biomarker. In children, the drug helps to restore growth and sexual development indicators.
Status : Eʼlon qilindi Source of funding: Jamoat Fondi Mablag'lari
Documents
Tender Notice