Procurement Summary
Country : Brunei Darussalam
Summary : Provision of Outsourcing Clinical Laboratory Tests
Deadline : 23 Aug 2022
Other Information
Notice Type : Tender
TOT Ref.No.: 69956377
Document Ref. No. : KK/194/2022/LAB(TC)
Financier : Self Financed
Purchaser Ownership : Public
Tender Value : Refer Document
Purchaser's Detail
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Quotation are invited for Provision of Outsourcing Clinical Laboratory Tests for National Reference Haematology Laboratory Department of Laboratory Services, Ministry of Health for a Period of Three(3) Years Usage
Cytogenetics - Children
Chromosome Analysis
1 a. Peripheral blood test 3
2 b. Amniotic fluid test 1
3 c. Fetal blood test 1
4 d. Product of conception test 1
5 e. Bone marrow test 1
6 f. Leukemic blood test 1
Chromosome Microarray Analysis
7 CMA test 5
FISH with chromosome Analysis
8 a. DiGeorge Region Probe test 1
9 b. Williams Region Probe test 1
10 c. PWS/AS Region Probe test 1
11 d. Wolf Hirschhorn Region Probe test 1
12 e. Cri du Chat Region Probe test 1
13 f. 22q13 Deletion Probe test 1
14 g. 13q14 Patau Region Probe test 1
15 h. 21q22. 13-q22.2 Down Region Probe test 1
16 i. Centromeric 18 Probe test 1
17 j. Centromeric x and Y probe test 1
18 k. SRY Probe test 1
FISH - (METAPHASE) ADD ON
19 a. DiGeorge Region Probe test 1
20 b. Williams Region Probe test 1
21 c. PWS/AS Region Probe test 1
22 d. Wolf Hirschhorn Region Probe test 1
23 e. Cri du Chat Region Probe test 1
24 f. 22q13 Deletion Probe test 1
25 g. 13q14 Patau Region Probe test 1
26 h. 21q22. 13-q22.2 Down Region Probe test 1
27 i. Centromeric 18 Probe test 1
28 j. Centromeric x and Y probe test 1
29 k. SRY Probe test 1
FISH - INTERPHASE DIRECT
30 a. Trisomy 13 test 1
31 b. Trisomy 21 test 1
2
USER-S REQUIREMENTS
NO ITEM DESCRIPTIONS AND SPECIFICATIONS PACKAGING
SIZE
TOTAL
ESTIMATE USAGE /
YEAR
32 c. Trisomy 18 test 1
33 d. Centromerix x and Y Probe test 1
34 e. Aneuploidy Panel (Trisomy 13, 18, 21, x and
Y)
test 1
35 f. Aneuploidy Panel (Trisomy 13, 18, 21, x and Y)
on paraffin
test 1
Cytogenetics - Adult
Cancer Chromosomal Karyotyping
36 a. Bone Marrow test 150
37 b. Peripheral blood test 20
38 c. Effusions, CSF test 1
FISH Panel test
39 a. FISH Panel Multiple Myeloma test 30
40 b. FISH Panel Chronic Lymphocytic Leukemia test 5
41 c. FISH Panel Myelodysplastic Syndrome test 15
FISH with chromosomal karytotyping (Add on
FISH)
42 a. FISH Add on for 1 probe test 1
43 b. FISH Add on for 2 probes test 1
44 c. FISH Add on for 3 probes test 1
FISH without chromosomal karytotyping
(Interphase FISH)
45 a. FISH Interphase on for 1 probe test 1
46 b. FISH Interphase on for 2 probes test 1
47 c. FISH Interphase on for 3 probes test 1
HLA
HLA Typing
48 HLA ABC Low resolution test 45
49 HLA DRB/DQB low resolution test 50
50 HLA ABC high resolution test 2
51 HLA DRB1 high resolution test 2
52 HLA DQB1 high resolution test 2
53 HLA DPB1 high resolution test 2
54 Add on charge for more than 1 donor HLA Typing test 10
HLA Antibody Screen (Panel Reactive
Antibody)
test
55 HLA Class I & II by Flow test 30
HLA Antibody Identidication (Donor Specific
Antibody)
test
56 HLA Class I only test 2
57 HLA Class II only test 2
58 HLA Class I & II test 35
59 C1q HLA Class I only test 1
60 C1q HLA Class I only test 1
Crossmatch (for HLA) test
61 Complement Dependent Cytotoxicity (CDC) test 45
62 CDC - auto crossmatch test 45
63 Flow with pronase test 35
64 Flow wtthout pronase test 5
65 HLA-B27 CDC (Screening) test 10
66 HLA B-27 HR (PCR) test 2
3
USER-S REQUIREMENTS
NO ITEM DESCRIPTIONS AND SPECIFICATIONS PACKAGING
SIZE
TOTAL
ESTIMATE USAGE /
YEAR
67 HLAB*5701 test 150
FLOW CYTOMETRY ASSAY - Children
68 a. Diagnosis/Relapse Phenotyping only test 10
69 b. Diagnosis/Relapse phenotyping plus
identification of MRD markers
test 10
70 c. Identification of MRD Markers only test 5
71 d. MRD assay test 15
Flow Cytometry - Adult 1
73 Immunophenotyping by Flow Cytometry 1
72 PNH Panel test 10
73 HS EMA Binding Test test 1
74 Blast Lineage Panel tes 25
75 Lymphoma Screening Panel test 22
76 Lymphoma Screening Panel for Small Sample test 7
77 Myeloma/Plasma Cell Dyscrasia Panel
(Diagnosis)
test 30
78 Myeloma/Plasma Cell Dyscrasia Panel (Followup)
test 2
79 B-ALL Panel test 17
80 B-ALL Panel Follow up Panel test 2
81 B-ALL Panel Follow up Panel (post Anti-CD19
theraphy/CAR-T)
test 2
82 B-ALL MRD Panel post anti CD-19
immunotherapy
test 1
83 T-ALL Follow up Panel test 5
84 Myeloid Neoplasm Basic Panel (Diagnostics) test 40
85 Myeloid Neoplasm/AML Basic Panel (Follow up) test 7
86 AML Add-on Panel test 15
87 AML Follow up Full Panel test 2
88 B-CLPD Panel test 15
89 T-CLPD Panel test 5
90 NK-CLPD Panel test 1
91 Flow 1 Myeloma test 2
Molecular - Children test
92 ALL Diagnostic Recommended package test
93 1.1 MRD Screening by Next Generation
Sequencing (NGS)
test
1
94 2.1 Oncogene Fusion Screening by RNA
Sequencing
test
1
95 3.1.1 Molecular prognostic marker - ALL test 1
96 4.1 Thiopurine (MP/AZA) Pharmacogenetics test 1
ALL Diagnostic Standard package
97 1.1 MRD Screening by Next Generation
Sequencing (NGS)
test
1
98 2.2 Oncogene Fusion Screening - ALL Panel test 1
99 2.4 Oncogene Fusion Screening - MLL Panel test 1
100 3.1.1 Molecular prognostic marker - ALL test 1
4
USER-S REQUIREMENTS
NO ITEM DESCRIPTIONS AND SPECIFICATIONS PACKAGING
SIZE
TOTAL
ESTIMATE USAGE /
YEAR
101 3.2 Molecular prognostic marker - ETP-ALL Panel test 1
102 4.1 Thiopurine (MP/AZA) Pharmacogenetics test 1
Minimal Residual Disease (MRD) in ALL
103 1.1 MRD Screening by Next Generation
Sequencing (NGS)
test 5
1.2 MRD Timepoint
104 1.2.1 Real time Quantitative PCR test 5
105 1.2.2 Droplet Digital PCR test 5
106 1.2.3 Next Generation Sequencing Quantitation test 1
Oncogene Fusion Transcript (OFT) Screening
107 2.1 RNA Sequencing (ALL/AML) test 1
108 2.2 ALL Panel test 15
109 2.3 AML Panel test 15
110 2.4 MLL Panel test 1
111 2.5 Single OFT (ALL/AML) test 5
112 2.6 Quantitation by Droplet Digital PCR test 3
Molecular Prognostic Markers
113 3.1 ALL Panel 3.1.1 MPA SALSA P335 test 5
3.2 ETP-ALL/AML Panel
114 3.2.1 FLT3-ITD (Allelic Ratio) test 5
Genotyping Services
115 4.1 Thiopurine (MP/AZA) Pharmacogenetics test 5
116 4.2 KIR Genotyping test 1
Molecular Tests - Adult/General
117 ABL1 Kinase Domain Mutation Screen test 1
118 Acute Lymphoblastic Leukemia (ALL) Panel test 15
119 Acute Myeloid Leukemia (AML) Panel test 15
120 BCR ABL Kinase Domain Mutation test 5
121 BCR ABL Qualitative test 55
122 BCR ABL Quantitative test 55
123 BRAF Mutation Detection test 1
124 Calreticulin, CALR Exon 9 Mutation Detection test 20
125 CEBPA Mutation Detection test 3
126 Cholestasis Panel test 1
127 Crouzon Syndrome (FGFR 2 & 3) test 1
128 DiGeorge Syndrome test 1
129 DNA Analysis of Alpha-Thalassaemia mutation test 5
130 DNA Analysis of Beta-Thalassaemia mutation test 5
131 DNA sequencing of Alpha globin genes test 1
132 DNA sequencing of Beta globin genes test 1
133 F1PL1-PDGFR test 15
134 Fanconi Anaemia test 1
135 FLT3-ITD test 5
136 FLT3-NPM1 Mutational Panel test 7
137 FLT3-NPM1-CEBPA Mutational Panel test 15
138 FLT3-NPM1-KIT Mutational Panel test 2
139 Fragile x test 1
140 Fraser Syndrome test 1
5
USER-S REQUIREMENTS
NO ITEM DESCRIPTIONS AND SPECIFICATIONS PACKAGING
SIZE
TOTAL
ESTIMATE USAGE /
YEAR
141 Friedrich's Ataxia test 1
142 Gene Mapping (ɑ - Thalassaemia, prenatal) test 1
143 Gene Mapping (ß - Thalassaemia, prenatal) test 1
144 Haemachromatosis (HFE) test 1
145 Huntington disease test 1
146 Immunoglobulin Heavy Chain Gene
Rearrangement
test 1
147 JAK2 Exons 12 & 13 Mutation Detection test 50
148 JAK2 V617F Mutation Detection test 10
149 JAK2-CALR Mutational Analysis test 1
150 JAK2-MPL-CALR Mutational Analysis test 1
151 KIT Mutation Detection test 3
152 KRAS Mutation Detection test 1
153 Malaria Parasites identification molecular test 1
154 Marfan Syndrome test 1
155 Methylenetetrahydrofolate reductase (MTHFR)
gene
test
2
156 MPL Exon 10 Mutation Detection test 5
157 Multiple Endocrine Neoplasia Type 2A/FMTC test 1
158 Multiple Endocrine Neoplasia Type 2B test 1
159 MYD88 L265P Mutation Detection test 1
160 Myeloid Neoplasm NGS Panel for
Myeloproliferative Neoplasm (MPN)
test 1
161 Myelopid Neoplasm NGS Panel for Acute
Myeloid Leukemia (AML)
test 1
162 Myotonic dystrophy test 1
163 Neurofibromatosis Type 1/Type 2 test 1
164 NF-1 Gene test 1
165 Non-invasive prenatal screening test 1
166 Noonan's Syndrome test 1
167 Pantothenate Kinase Assoc Neurodegenaration test 1
168 PML RARA test 10
169 PORCN Gene Mutation test 1
170 Prader Willi/Angelman Syndrome (MS-PCR) test 1
171 Rett's Syndrome (MECP2) test 1
172 Single Oncogene Fusion test 5
173 Spinal muscular atrophy test 1
174 Spinocerebellar ataxia (SCA) type test 1
175 Spinocerebellar ataxia screen test 1
176 T-Cell Receptor Gene Rearrangement - ɣ cahin test 7
177 Tubercous Sclerosis test 1
178 VNTR test 5
Others
179 PF4 ASSAY test 10
COAGULATION SECTION
180 ADAMTS13 Assay test 5
181 Factor V test 1
182 Factor V Leiden test 10
Quotation Fee: $500.00
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