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DEPT OF DEFENSE | DEFENSE HEALTH AGENCY (DHA) has floated a tender for PANDHA-25-P-0000_003354 DNA Aptamer-based Therapeutic Development. The project location is USA and the tender is closing on 01 Apr 2025. The tender notice number is PANDHA-25-P-0000_003354, while the TOT Ref Number is 116778302. Bidders can have further information about the Tender and can request the complete Tender document by Registering on the site.
Procurement Summary
Country : USA
Summary : PANDHA-25-P-0000_003354 DNA Aptamer-based Therapeutic Development
Deadline : 01 Apr 2025
Other Information
Notice Type : Tender
TOT Ref.No.: 116778302
Document Ref. No. : PANDHA-25-P-0000_003354
Financier : Self Financed
Purchaser Ownership : Public
Tender Value : Refer Document
Purchaser's Detail
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Description
The objective of this contract is to conduct a two-year study on conjugated aptamers as antimicrobial agents to produce DNA aptamers conjugated with C1q- and Fc-domain proteins to create a biologic therapeutic with immunomodulatory antimicrobial activity against bacterial pathogens for wound infection. This shall include producing DNA aptamers that bind to the bacterial pathogen Pseudomonas aeruginosa; conjugating DNA aptamers to recombinant C1q protein and to recombinant IgG Fc domain protein to produce C1q- and Fc-conjugated DNA aptamers; validating that C1q- and Fc-conjugated DNA aptamers bind to Pseudomonas aeruginosa; and delivering C1q- and Fc-conjugated DNA aptamers to WRAIR, AFRIMS for testing, located in Bangkok, Thailand.
Active Contract Opportunity
Notice ID : PANDHA-25-P-0000_003354
Related Notice
Department/Ind. Agency : DEPT OF DEFENSE
Sub-tier : DEFENSE HEALTH AGENCY (DHA)
Office: ARMY MED RES ACQ ACTIVITY
General Information
Contract Opportunity Type: Sources Sought (Original)
Original Published Date: Mar 25, 2025 08:03 am EDT
Original Response Date: Apr 01, 2025 10:00 am EDT
Inactive Policy: 15 days after response date
Original Inactive Date: Apr 16, 2025
Initiative: None
Classification
Original Set Aside:
Product Service Code: B537 - SPECIAL STUDIES/ANALYSIS- MEDICAL/HEALTH
NAICS Code: 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Place of Performance: BANGKOK, TH-10 THA
Documents
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