Notice of Intent to Sole Source - 10x Genomics Tender, USA - 125272484

Procurement Summary

Country: USA

Summary: Notice of Intent to Sole Source - 10x Genomics

Deadline: 10 Sep 2025

Other Information

Notice Type: Tender

TOT Ref.No.: 125272484

Document Ref. No.: NOI-CC-25-008681

Financier: Self Financed

Purchaser Ownership: Public

Tender Value: Refer Document

Purchaser's Detail

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Tender Details

Description

This is a notice of intent, not a request for a quotation. A solicitation document will not be issued and quotations will not be requested.

This procurement is for 10x Genomics 5- v3 single cell sequencing kits, TCR amplification kits, and Single Cell Multiome ATAC + Gene Expression kits. The kits are composed of reagents for the isolation and amplification of uniquely barcoded ribonucleic acid (RNA) and chromatin accessible regions from individual cells. The 10x Genomics single cell sequencing of immune cells enables high-throughput simultaneous and accurate determination of the nature of an immune response to an infection (what the cells are doing and which cells are doing it). The 10x Genomics platform uses microfluidics to separate individual cells into an emulsion with single gel beads and labels the RNA from each cell with a unique barcode for partitioning into libraries for sequencing. The single cell sequencing kit is proprietary to 10x Genomics, the original equipment manufacturer of the 10x Genomics platform.

These supplies will be used for a study of the immune response to Pneumocystis infection in mouse animal models, as well as studying histone modifications, to better under the Pneumocystis biology. Animals will be infected with the fungal pathogen using a co-housing exposure model, and then followed up overtime, collecting lung tissue samples which will be used to assess changes in gene expression overtime. Single cell sequencing will allow for the profiling of immune cell subsets and B cell receptor sequences during infection, and gene expression changes in the fungal pathogen.

10x Genomics is the sole manufacturer of the 10x Genomics platform and single cell sequencing reagents. Other manufacturer-s single cell single reagents are not compatible for use with the 10x Genomics platform. The Critical Care Medicine Department has independently modified and validated the recommended protocols provided by the 10x Genomics. Any...
Active Contract Opportunity
Notice ID : NOI-CC-25-008681
Related Notice
Department/Ind. Agency : HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier : NATIONAL INSTITUTES OF HEALTH
Office: NATIONAL INSTITUTES OF HEALTH - CC
General Information
Contract Opportunity Type: Special Notice (Updated)
Updated Published Date: Aug 27, 2025 01:33 pm EDT
Original Published Date: Aug 27, 2025 01:29 pm EDT
Updated Response Date:
Original Response Date:
Inactive Policy: Manual
Updated Inactive Date: Sep 10, 2025
Original Inactive Date: Sep 03, 2025
Initiative: None

Classification
Original Set Aside:

Product Service Code: 6550 - IN VITRO DIAGNOSTIC SUBSTANCES, REAGENTS, TEST KITS AND SETS
NAICS Code: 325413 - In-Vitro Diagnostic Substance Manufacturing

Place of Performance: Bethesda, MD 20892 USA

Documents

 Tender Notice

JOFOC-Under-the-SAT-GlideScope-2025.docx