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The HEALTH AND HUMAN SERVICES, DEPARTMENT OF | NATIONAL INSTITUTES OF HEALTH has issued a Tender notice for the procurement of a Nih Tetramer Core Facility in the USA. This Tender notice was published on 31 Mar 2026 and is scheduled to close on 14 Apr 2026, with an estimated Tender value of Refer Document. Interested bidders can access detailed Tender information, eligibility criteria, and complete bidding documents by referencing TOT Ref No. 138713446, while the tender notice number is 75N93026R00006 and Registering on the platform.
Procurement Summary
Country: USA
Summary: Nih Tetramer Core Facility
Deadline: 14 Apr 2026
Posting Date: 31 Mar 2026
Other Information
Notice Type: Tender
TOT Ref.No.: 138713446
Document Ref. No.: 75N93026R00006
Competition: ICB
Financier: Self Financed
Purchaser Ownership: Public
Tender Value: Refer Document
Purchaser's Detail
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Login to see detailsTender Details
Background
The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), of the Department of Health and Human Services (DHHS) supports research related to the basic understanding of microbiology and immunology leading to the development of vaccines, therapeutics, and medical diagnostics for the prevention, treatment, and diagnosis of infectious and immune-mediated diseases. As part of this mission, NIAID requires continued operation of the NIH Tetramer Core Facility (TCF). The TCF is a centralized resource producing and distributing custom MHC multimer reagents for the biomedical research community. These reagents enable the sensitive and specific detection of antigen-specific T cells across a range of diseases, including autoimmunity, cancer, and infectious diseases. MHC multimers are powerful tools for the rapid, highly sensitive quantitation of antigen-specific T cells from blood or tissue samples. Traditional reagents are comprised of four identical biotinylated MHC molecules, each loaded with an antigen-specific peptide/ligand, tetramerized using a streptavidin-linked fluorophore (i.e., tetramers). Current production methods may also generate higher-order multimers, either as a byproduct of the multimerization process or through approaches specifically designed to produce MHC multimers with higher valency.
The TCF is an essential resource for the biomedical research community, enabling precise characterization of antigen-specific T cell populations. It plays a key role in research aligned with DHHS priorities, including the study and treatment of chronic and complex diseases, such as food allergies, autoimmune diseases, cancer, narcolepsy, organ transplantation, and Alzheimer-s Disease. These efforts are central to advancing DHHS- mission to enhance health outcomes, improve quality of life, and reduce the burden of disease through scientific innovation.
The NIH Tetramer Core Facility contract was initially aw...
Notice ID: 75n93026r00006
Department/Ind. Agency: health and human services, department of
Sub-tier: national institutes of health
Office: national institutes of health niaid
Product Service Code: an11 - health r&d services; health care services; basic research
NAICS Code: 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Inactive Dates: apr 29, 2026
Inactive Policy: 15 days after response date
Documents
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