Intent to Sole Source Lundquist Institue. VA DNA and medical study support. Tender

Procurement Summary

Country: USA

Summary: Intent to Sole Source Lundquist Institue. VA DNA and medical study support.

Deadline: 04 Aug 2025

Other Information

Notice Type: Tender

TOT Ref.No.: 123649620

Document Ref. No.: 36C24E25R0030

Financier: Self Financed

Purchaser Ownership: Public

Tender Value: Refer Document

Purchaser's Detail

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Tender Details

Description

The Veteran s Administration (VA) Office of Research and Development, Regional Procurement Office East in Pittsburgh, PA intends to negotiate on a sole source basis with The Lundquist Institute based in Torrance, CA on behalf of the VA Madison, WI VA Healthcare System. The requirement encompasses the development of standard procedures and comprehensive oversight, processing, and analysis of DNA samples for a multisite randomized controlled trial focused on genetic factors influencing blood pressure (BP) and arterial stiffness. The work is to be performed across three study sites: Madison WI, Nashville TN, and Alabama VA facilities. This contract requires the expertise of a specialized team to manage the genetic components of the trial, ensuring the integrity and quality of the genetic data collected. All services requested should be done at one facility to ensure data quality, streamlined data analysis, and to facilitate future analyses. The primary objective is to receive, handle, store, and analyze DNA samples to investigate the potential of a BP polygenic risk score (PRS) in predicting individual responses to BP targets, specifically regarding load-dependent arterial stiffness. This involves the meticulous handling of approximately 250 DNA samples over the contract period, utilizing advanced genotyping techniques and rigorous statistical analysis to identify significant genetic predictors of BP regulation and arterial stiffness.The specific work to be performed includes:Develop manual of procedures for proposed workReceive, store and track packed-cell samplesDNA Isolation and Genotyping Genetic analysis and appropriate reportingGeneral consultation and oversight of genetic aspects of the protocol.Task 1 Develop the MOPs for the following Sub tasks: 1) Preparing packed-cell samples for shipping2) Receiving/handling/storing/tracking of packed cell samples3) Sample tracking/Barcode/Manifest creation4) DNA Isolation and GenotypingSubtask 1) Preparing ...
Active Contract Opportunity
Notice ID : 36C24E25R0030
Related Notice
Department/Ind. Agency : VETERANS AFFAIRS, DEPARTMENT OF
Sub-tier : VETERANS AFFAIRS, DEPARTMENT OF
Office: RPO EAST (36C24E)
General Information
Contract Opportunity Type: Special Notice (Original)
Original Published Date: Jul 30, 2025 10:47 am EDT
Original Response Date: Aug 04, 2025 10:00 am EDT
Inactive Policy: Manual
Original Inactive Date: Aug 14, 2025
Initiative: None

Classification
Original Set Aside:
Product Service Code: R405 - SUPPORT- PROFESSIONAL: OPERATIONS RESEARCH/QUANTITATIVE ANALYSIS
NAICS Code: 541713 - Research and Development in Nanotechnology

Place of Performance:

Documents

 Tender Notice

36C24E25R0030.docx