Procurement Summary
Country: France
Summary: High-Throughput Imaging Screening Services on Human Placental Tissue and Cell Models and Evaluation of Antiviral Compounds as Part of the Vertical Project
Deadline: 01 Jun 2026
Posting Date: 01 Jun 2026
Other Information
Notice Type: Tender
TOT Ref.No.: 142405246
Document Ref. No.: Infinity-CM-Vertical
Competition: ICB
Financier: Self Financed
Purchaser Ownership: Public
Tender Value: Refer Document
Purchaser's Detail
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Tender Details
This contract is part of the VERTICAL research project (Mechanistic characterization of novel host and viral factors for therapeutic interventions targeting transplacental transmission of Flaviviruses), funded by PEPR Maladies Emerging Infectious Diseases (EIM), and in particular its Work-Package 4 (WP4). The VERTICAL project aims to elucidate the molecular and cellular mechanisms (host and viral factors) which govern the transmission of Flaviviruses (such as viruses Zika, Usutu, Dengue or West Nile) from mother to fetus during pregnancy. The major challenge is to identify new therapeutic targets (in particular to evaluate the impact of placental extracellular vesicles) to prevent infections. congenital and protect fetal development. This purchase is specifically dedicated to the operational implementation of WP4. This component of the project aims to: - - - Develop and operate a high-throughput cellular imaging (HCS) technological platform to model viral infection at the mother-child interface. Characterize the biological impact of placental extracellular vesicles (EVs) on viral transmission. Identify, through pharmacological screening, compounds capable of inhibiting viral replication in complex human models. The success of this project relies on the service provider's ability to combine cutting-edge expertise in automated imaging with the handling of highly sensitive human biological samples. (including fresh placental explants). This service requires strong technical integration with the teams of the Inserm Infinity institute, project leader, in order to transform ex vivo biological models into quantitative screening data. and reproducible.
Lot(s):- Table of information on the different lots of the notice in 3 columns: Lot number, Title and Submission deadline. Lot number Title Offer selection criteria 1 High-throughput imaging screening services on tissue models and human placental cells and evaluation of antiviral compounds as part of the VERTICAL project Type of procedure:- Procedure adapted to an envelope Deadline for submission of envelopes: - June 1, 2026 12:00 (Paris time)
Documents
Tender Notice