Generative Optogenetics GO Tender in USA - 132419056

Procurement Summary

Country: USA

Summary: Generative Optogenetics GO

Deadline: 26 Feb 2026

Posting Date: 20 Dec 2025

Other Information

Notice Type: Tender

TOT Ref.No.: 132419056

Document Ref. No.: DARPA-PS-26-10

Financier: Self Financed

Purchaser Ownership: Public

Tender Value: Refer Document

Purchaser's Detail

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Tender Details

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative concepts to design a protein complex that can be expressed in vivo (i.e., in a living cell) and responds to optical signals to synthesize a corresponding DNA or RNA sequence. This technology should enable massless transfer of genetic information to cells expressing the protein complex via a template-free mechanism that incorporates nucleotide bases in response to specific optical signals (e.g., different wavelengths of light). The GO program is focused on two main Research Objectives (ROs): (1) achieving the core capability of synthesizing DNA/RNA directly in living cells using optical signals, and (2) developing error mitigation methods that ensure high-fidelity nucleic acid synthesis. The acquisition process for GO will proceed through a two-stage process, starting with (1) written abstracts which will inform invitations to brief (2) an Oral Proposal Package (OPP) at DARPA.
Notice ID: darpa-ps-26-10
Department/Ind. Agency: dept of defense
Sub-tier: defense advanced research projects agency (darpa)
Office: def advanced research projects agcy
Product Service Code: ac12 - national defense r&d services; department of defense - military; applied research
NAICS Code: 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Inactive Dates: mar 28, 2026
Inactive Policy: manual

Documents

 Tender Notice