Procurement Summary
Country: USA
Summary: Dow Amyotrophic Lateral Sclerosis Research Program, Therapeutic Development Award
Deadline: 30 Sep 2026
Posting Date: 05 May 2026
Other Information
Notice Type: Tender
TOT Ref.No.: 140656175
Document Ref. No.: HT942526ALSRPTDA
Competition: ICB
Financier: Self Financed
Purchaser Ownership: Public
Tender Value: Refer Document
CPV Classification
73110000 - Research services
33642200 - Corticosteroids for systemic use
33693300 - Addiction treatment
Purchaser's Detail
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Login to see detailsTender Details
Summary: The Fiscal Year 2026 (Fy26) Amyotrophic Lateral Sclerosis Research Program (Alsrp) Therapeutic Development Award (Tda) Supports Research Ranging From Preclinical Validation Of Therapeutic Leads Through U.S. Food And Drug Administration (Fda) Investigational New Drug (Ind)-Enabling Studies. The Proposed Studies Are Expected To Be Empirical In Nature And Product-Driven. Applicants With Limited Amyotrophic Lateral Sclerosis (Als) Experience Are Strongly Encouraged To Include Collaborators With Substantial Experience In The Relevant Als Model Systems, Endpoints And Pathophysiology.Applications Supported By This Award Must Begin With Lead Compounds In Hand And Must Already Demonstrate Proof-Of-Concept Efficacy Data In At Least One Appropriate Preclinical Model System Of Als, Including Whole-Animal And Cellular Model Systems.Distinctive Features: Mechanism-Specific, Predictive/Cohort-Selective, Target Engagement And Pharmacodynamic Biomarker Development, In Parallel To The Main Therapeutic Effort, Is A Critical Component Of The Fy26 Alsrp Therapeutic Development Award. If Appropriate Mechanism-Specific Biomarkers Are Already Available Or Currently In Development, How The Existing Biomarkers Will Improve Trial Design, Patient Selection, And Efficiency Or Interpretation Of The Proposed Als Therapeutic Approach Must Be Apparent In The Application. Development Of Biomarkers For The Purposes Of Diagnosis, Prognosis, Or Measurement Of General Disease Progression Without Consider...
Posted Date: 2026-05-04 00:00:00
Funding instrument type: Grant
Documents
Tender Notice