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DEPT. OF THE ARMY -- USAMRAA has floated a tender for Dod Amyotrophic Lateral Sclerosis, Therapeutic Development Award. The project location is USA and the tender is closing on 27 Aug 2025. The tender notice number is HT942525ALSRPTDA, while the TOT Ref Number is 117933280. Bidders can have further information about the Tender and can request the complete Tender document by Registering on the site.
Procurement Summary
Country: USA
Summary: Dod Amyotrophic Lateral Sclerosis, Therapeutic Development Award
Deadline: 27 Aug 2025
Other Information
Notice Type: Tender
TOT Ref.No.: 117933280
Document Ref. No.: HT942525ALSRPTDA
Financier: Self Financed
Purchaser Ownership: Public
Tender Value: USD 9800000
Purchaser's Detail
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Login to see detailsTender Details
Summary: The Fiscal Year 2025 (Fy25) Amyotrophic Lateral Sclerosis Research Program (Alsrp) Therapeutic Development Award (Tda) Supports Research Ranging From Preclinical Validation Of Therapeutic Leads Through Food And Drug Administration (Fda) Investigational New Drug (Ind)-Enabling Studies. The Proposed Studies Are Expected To Be Empirical In Nature And Product Driven. Applicants With Limited Amyotrophic Lateral Sclerosis (Als) Experience Are Strongly Encouraged To Include Collaborators With Substantial Experience In The Relevant Als Model Systems, Endpoints, And Pathophysiology.Applications Supported By This Award Must Begin With Lead Compounds In Hand And Must Already Demonstrate Proof-Of-Concept Efficacy Data In At Least One Appropriate Preclinical Model System Of Als, Including Whole Animal And Cellular Model Systems. Distinctive Features: Mechanism-Specific, Predictive/Cohort-Selective, Target Engagement, And Pharmacodynamic Biomarker Development, In Parallel To The Main Therapeutic Effort, Is A Critical Component Of The Fy25 Alsrp Therapeutic Development Award. If Appropriate Mechanism-Specific Biomarkers Are Already Available Or Currently In Development, How The Existing Biomarkers Will Improve Trial Design, Patient Selection, And Efficiency Or Interpretation Of The Proposed Als Therapeutic Approach Must Be Apparent In The Application. Development Of Biomarkers For The Purposes Of Diagnosis, Prognosis, Or Measurement Of General Disease Progression Without Considerat...
Opportunity Category : Discretionary
Opportunity Category Explanation :
Funding Instrument Type : Grant
Category of Funding Activity : Science and Technology and other Research and Development
CFDA_Number :
Posted Date : Apr 18, 2025
Last Updated Date : Apr 18, 2025
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