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Development of a Patient Derived Ryr-1 Myopathy Model Tender, USA - 97082353

HEALTH AND HUMAN SERVICES, DEPARTMENT OF has floated a tender for Development of a Patient Derived Ryr-1 Myopathy Model. The project location is USA and the tender is closing on 23 Feb 2024. The tender notice number is NOINIH6891599, while the TOT Ref Number is 97082353. Bidders can have further information about the Tender and can request the complete Tender document by Registering on the site.

Procurement Summary

Country : USA

Summary : Development of a Patient Derived Ryr-1 Myopathy Model

Deadline : 23 Feb 2024

Other Information

Notice Type : Tender

TOT Ref.No.: 97082353

Document Ref. No. : NOINIH6891599

Competition : ICB

Financier : Self Financed

Purchaser Ownership : Public

Tender Value : Refer Document

Purchaser's Detail

Purchaser : HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Contracting Office Address : Bethesda, MD 20892
Primary Point of Contact : van v holley
holleyv@od.nih.gov
Phone Number 3015949439

Secondary Point of Contact : Sharmaine Fagan
sharmaine.fagan@nih.gov
Phone Number 3015943744
USA
Email :holleyv@od.nih.gov

Tender Details

Description

This is a Notice of Intent, not a request for proposal. National Institute of Health (NIH)/National Institute of Nursing Research (NINR) intends to negotiate on an other than full and open competition basis with Hesperos, Inc. 12501 Research Parkway, Suite 100 Orlando, FL 32826, to provide provide Development of a Patient Derived RYR-1 Myopathy Model to Identify Disease Related Functional Deficits.

The purpose of the procurement is for the vendor to develop a patient derived RYR-1 myopathy model using Hesperos- Human-on-a-Chip micro-physiological systems. The Skeletal Muscle (SkM) model for RYR-1 associated myopathies will be developed by utilizing NIH-NINR sourced patient myoblasts and resultant myotubes for further downstream functional evaluation utilizing a Hesperos single-organ system. Patient cells will be evaluated for muscle function compared to healthy (Hesperos Sourced - ND41865) iPSC myoblasts. Myoblasts will be plated on silicon cantilever arrays and allow to fuse into myotubes to obtain contractile force measurements to identify SkM dysfunction associated with the RYR-1 myopathy phenotype.

Scope Contractor will independently provide Development of a Patient Derived RYR-1 Myopathy Model to Identify Disease Related Functional Deficits.

The statutory authority for this sole source requirement is 41 U.S.C. 253 (c) (1) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A SOLICITATION FOR COMPETITIVE QUOTATIONS. All responsible sources that could provide the required services may submit a capability statement that will be considered by email to Ms. Van Holley at holleyv@od.nih.gov by 10:00am eastern standard time Friday, February 23, 2024. All responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the d...
Active Contract Opportunity Notice ID NOINIH6891599 Related Notice Department/Ind. Agency HEALTH AND HUMAN SERVICES, DEPARTMENT OF Sub-tier NATIONAL INSTITUTES OF HEALTH
General Information
Contract Opportunity Type: Special Notice (Original)
All Dates/Times are: (UTC-05:00) EASTERN STANDARD TIME, NEW YORK, USA
Original Published Date: Feb 15, 2024 01:30 pm EST
Original Response Date: Feb 23, 2024 10:00 am EST
Inactive Policy: 15 days after response date
Original Inactive Date: Mar 09, 2024
Initiative: None

Classification
Original Set Aside: Total Small Business Set-Aside (FAR 19.5)
Product Service Code: R499 - SUPPORT- PROFESSIONAL: OTHER
NAICS Code:
Place of Performance: Bethesda, MD 20892 USA