Custom-Made Gmp Peptides Tender, Netherlands - 115072607

Procurement Summary

Country : Netherlands

Summary : Custom-Made Gmp Peptides

Deadline : 06 Apr 2025

Other Information

Notice Type : Tender

TOT Ref.No.: 115072607

Document Ref. No. : 114557-2025

Financier : Self Financed

Purchaser Ownership : Public

Tender Value : EUR 1

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Tender Details

The Department of Medical BioSciences from Radboudumc has been award a KWF grant for the PROTECT-lynch study. The main goal of the PROTECT-lynch study is a new treatment option for LS patients significantly improving the quality of life of LS patients and most likely the prognosis (occurrence of Lynch-related cancer(s). Standard care for healthy LS patients currently consists of undergoing intensive surveillance programs that do not guarantee timely detection of one or more Lynch-related cancers at a treatable stage. The PROTECT-lynch study may change this with its preventive dendritic cell therapy. To prepare the intended dendritic cell (DC) product for the PROTECT-lynch study, several different short GMP peptides are required in drug substance (Active Pharmaceutical Ingredient, API) quality. As the Medical BioSciences department, we have extensive experience in the preparation of DC products in collaboration with the Pharmacy department, in which comparable peptides were present as important active substances. The specific peptides are always selected based on suitable targets in the intended patient population for which the treatment is being developed. In the case of the PROTECT-lynch study, a comprehensive screening analysis was conducted to identify common gene mutations and their occurrence rates in tumors among a broad patient group with Lynch-related cancers, categorized by HLA type. The selected tumor-specific peptides, so-called neoantigens, were then ordered from ...
Document Type: Prior Information Notice
Reference Number: Market consultation Custom-made GMP peptides
Contract Type: supplies
Estimated Value: 1 - EUR
Authority Type: pub-undert
Doc Title: Custom-made GMP peptides
Dispatch Date: 2025-02-18
Publish Date: 2025-02-20
Submission Date: 2025-04-06

Documents

 Tender Notice