Contract for the Provision for the Manufacture Tender - 127148380

Procurement Summary

Country: Ireland

Summary: Contract for the Provision for the Manufacture of Vaccine Antigen

Deadline: 16 Oct 2025

Posting Date: 27 Sep 2025

Other Information

Notice Type: Tender

TOT Ref.No.: 127148380

Document Ref. No.: 6637271

Competition: ICB

Financier: Self Financed

Purchaser Ownership: Public

Tender Value: Refer Document

CPV Classification

33651600 - Vaccines
33600000 - Pharmaceutical products

Purchaser's Detail

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Tender Details

UCD has developed a series of bacterial antigens which have proven effective in proof-of-concept studies and which the aim is to further develop and translate to humans. The lead target antigen is 22 kDa cytosolic bacterial protein and is currently His-tagged to facilitate affinity purification. UCD have developed a lab-scale expression and purification protocol, which will be provided to the successful contractor. We require contract protein manufacture and purification services. The purpose of the work is to appropriately scale-up the antigen to produce ~200mg batches of protein at a standard that will confirm feasibility of technology transfer and that can be used in GLP toxicology studies in mice, to ensure safety of the developed product. Ultimately, UCD would like the process to be amenable to production in a GMP facility in the future.
Procedure : Open

Publication Date : 16/10/2025

Deadline : 16/10/2025 00:00:00

Documents

 Tender Notice