Automated Cryo-EM Sample Preparation Instrument Tender, USA - 126561867

Procurement Summary

Country: USA

Summary: Automated Cryo-EM Sample Preparation Instrument

Deadline: 19 Sep 2025

Posting Date: 18 Sep 2025

Other Information

Notice Type: Tender

TOT Ref.No.: 126561867

Document Ref. No.: 75P00125Q00071

Financier: Self Financed

Purchaser Ownership: Public

Tender Value: Refer Document

Purchaser's Detail

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Tender Details

Description

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only.

Background: The Structural Biology Core (SBC), Virology Laboratory (VL), Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) uses a structure-based approach for developing antibody therapeutics and vaccines for infectious diseases, including but not limited to COVID-19, HIV-1, malaria, flu, and RSV. The structural analysis of pathogen proteins, antibodies, and vaccines is essential to current and future SBC research. It requires high-resolution cryo-EM data attainable only with high-quality samples. Currently, SBC relies on manual plungers for the preparation of cryo-EM grids, which can yield suboptimal results, particularly with challenging samples. The adoption of automated, non-blotting technology offers a promising solution to this issue. To meet the specialized needs of SBC VRC, SBC needs to acquire the Chameleon Cryo-EM Sample Preparation Instrument or equivalent.

Purpose and Objectives: The purpose of this requirement is to purchase the Chameleon Cryo-EM Sample Preparation Instrument or equivalent.

Project requirements: The followin...
Active Contract Opportunity
Notice ID : 75P00125Q00071
Related Notice
Department/Ind. Agency : HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier : OFFICE OF THE ASSISTANT SECRETARY FOR ADMINISTRATION (ASA)
Office: PROGRAM SUPPORT CENTER ACQ MGMT SVC
General Information
Contract Opportunity Type: Sources Sought (Original)
Original Published Date: Sep 17, 2025 08:40 am EDT
Original Response Date: Sep 19, 2025 10:00 am EDT
Inactive Policy: 15 days after response date
Original Inactive Date: Oct 04, 2025
Initiative: None

Classification
Original Set Aside: No Set aside used
Product Service Code: 6640 - LABORATORY EQUIPMENT AND SUPPLIES
NAICS Code: 334516 - Analytical Laboratory Instrument Manufacturing

Place of Performance: Rockville, MD 20857 USA

Documents

 Tender Notice