Procurement Summary
Country: Finland
Summary: A Mass Photometry System
Deadline: 10 Dec 2025
Posting Date: 10 Nov 2025
Other Information
Notice Type: Tender
TOT Ref.No.: 129805977
Document Ref. No.: 741767-2025
Financier: Self Financed
Purchaser Ownership: Public
Tender Value: EUR 260000
Purchaser's Detail
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Login to see detailsTender Details
The object of the procurement is a mass photometry system. Biocenter Oulu seeks a label-free optical measurement system which is capable of nanoparticle, including protein, molecular mass and mass distribution determination in native state (without surface immobilisation) with single molecule detection sensitivity/resolution, including possibility to measure high concentration samples. The system is used to study oligomerization state, biomolecular interactions, polymerization, sample composition, and purity. The mass photometer device must be able to measure mass of various biological nanoparticles including proteins and nucleic acids up to 20 nm size and with low sample amount. The system must enable measurement of different kinds of samples including high concentration (tens of micromolar) protein solutions. The mass photometry device must utilise attenuated optical interferometric back-scattering microscopy with reduction of signal to noise or signal to background ratio to determine mass of individual particles and mass distribution of a sample. When calibrated against known masses of same refractive index, the mass of unknown sample with similar refractive index is calculated from the interference between the light scattered from the molecule above the surface and the reflected light. The measurement is done on a slide or a chip that are not sample specific. Wide-field imaging camera is used for signal detection. The system will be part of the Structural Biology cor...
Document Type: Contract Notice
Reference Number: 572963
Contract Type: supplies
Estimated Value: 260000 - EUR
Authority Type: body-pl
Doc Title: A mass photometry system
Dispatch Date: 2025-11-07
Publish Date: 2025-11-10
Submission Date: 2025-12-10
Documents
Tender Notice