Contract notice: Microscopes Tender, Germany - 38230531

Procurement Summary

Country : Germany

Summary : Contract notice: Microscopes

Deadline : 20 Dec 2019

Other Information

Notice Type : Tender

TOT Ref.No.: 38230531

Document Ref. No. : 553474-2019

Competition : ICB

Financier : Self Financed

Purchaser Ownership : -

Tender Value : Refer Document

Purchaser's Detail

Purchaser : UNIVERSITÄTSKLINIKUM JENA
Office Name: Universitätsklinikum Jena
Address: Bachstraße 18
Town: Jena
Postal Code: 07743
Contact Point: Stabsstelle Vergabe

Phone: +49 3641-9320180
Fax: +49 3641-9320082
Germany
Email :vergabestelle@med.uni-jena.de
URL :http://www.uniklinikum-jena.de

Tender Details

Object of the contract
Microscopes

Description: Contract notice: Microscopes

Authority Type: Body governed by public law
Contact Nature: Supplies
Procedure: Competitive dialogue
Document: Contract notice
Regulation: European Union
Award criteria: The most economic tender
CPV code: 38510000, 38510000, 38510000
CPV Description: Microscopes.

2P-STED Microscope

Reference Number: 651.W.19.089

Obtaining a Modular Confocal STED Microscope with Pulsed 1 and 2 Photon Excitation and 4 STED Lasers.

Main Site: Jena University Hospital

The Confocal STED Microscope should be suitable in its basic configuration for multi-user operation and offer an experienced user the opportunity, after a short EinarThe STED microscope is to be modularly adaptable to the specific measurement conditions by means of exchangeable components. The requirements beyond the standard applications are:

Simultaneous 6-channel recording with pulsed excitation and STED:

The STED microscope is designed to measure the conformational dynamics of individual enzymes in vitro and in lecells using picosecond time-resolved Foerster resonance energy transfers (smFRET), homo-FRET and time-resolved fluorescence anisotropy. The full bandwidth of picosecond pulsed excitation with laser wavelengths from 440 nm to 640 nm for single-photon excitation (1P) must be included. The highest sensitive single-photon detection should be performed simultaneously in6 channels (for 3 spectral regions and each separated by anisotropy) take place. Preferred detectors are time-optimized APDs with the lowest possible dark counting rate (less than 100 counts / s). Ideally, in each case 2 of the pulsed lasers can be switched in freely configurable alternating excitation sequences in the nanosecond range (nsALEX or PIE),

3 pieces of pulsed STED laser adaptive beamforming:

The STED microscope is designed to excite fluorescent proteins (mNeonGreen or mScarlett) as well as the entire range of STED-suitable organic fluorophores with emission maxima from 500 nm to 700 nm with picosecond pulsed STED lasers at 590 nm and 775 nm. A third pulsed 660 nm STED laser is required for easy retrofitting. A programmable Spatial Light modulator (SLM) to enable the adjustment of the shape of the focus for 2D and 3D STED,

- multi-photon excitation for STED with 4-channel detection:

A tunable fs titanium sapphire laser system (TiSa) for two-photon excitation between 800 nm 1 300 nm must be coupled in and synchronized with the 3 pulsed STED lasers. 4 highly sensitive GaAsP photomultipliers are to be useddetect fluorescence lifetime and time resolved anisotropy measurements in two spectral ranges. These need not be read out simultaneously with the 6 APD detectors. The accompanying 4-channel TCSPC electronics must consist of synchronized modules with sub-picosecond time resolution,

- Extra microscope port for free-jet coupling 1 ultra-narrow band STED laser:

The STEDMicroscope must be modular designed so that the user can implement new STED methods on a suitable port of the microscope stand. In particular, a STED de-excitation with an ultra-fine-band laser system at 589 nm is required, which can be tuned exactly to the absorption line of a sodium vapor-filled gas cuvette. In addition, a multi-channel GaAsP PMT with TCSPC Erequired for the combination of fiber-based image scanning microscopy with STED in the z-dimension (ISM-STED).

- Proof registration commercial register.

- Identification of the company`s total turnover over the last 3 business years;

- Designation of permanent employees permanent employees in the last 3 business years for the service concerned,

- Unbedcertificate of conformity of the tax office,

certificate of authenticity of a credit institute approved by Bafin in Germany,

declaration of no objection by the trade association, self-declaration on the absence of exclusionary reasons according to -- 123, 124 GWB, self-declaration for submission in the case of order. Professional indemnity insurance with coverage amount per claim minat least EUR 1 000 000.00 for personal injury and damage to property.

Questions regarding the invitation to tender must be sent to the awarding authority exclusively via DTVP (see point 1.3). Questions will be answered anonymously and made available to all applicants.

For the application to participate, only the files placed under the heading "documents to be filled in by the company" are relevant.

Worth the awarding authorityIt is not an inadmissible double application if subcontractors are involved by different bidders. However, it is imperative that the subcontractor is not aware of the offer prices of the provider. This is to be assured by a legally binding declaration of the respective subcontractor towards the contracting authorityparticipation of subcontractors does not lead to a bidder (bidding consortium) being able to draw compelling conclusions on the bid price of another bidder (bidder consortium) (eg as a result of the overriding identity of the subcontractors.) In the event of an inadmissible double bid, the competition principle must be adhered to both interested bidders are excluded.

Bekanntmachungs ID: CXP4YYAD5ZE


Internet address (URL): http://www.uniklinikum-jena.de

Documents

 Tender Notice